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×Anthony J. Passannante Jr., (standing center), acting president of Hackensack Meridian Health Palisades Medical Center, and members of the Venino Family gather in front of the Wall of Honor that now includes a plaque to posthumously honor Thomas M. Venino, Sr. Anthony J. Passannante Jr., (standing center), acting president of Hackensack Meridian Health Palisades Medical Center, and members of the Venino Family gather in front of the Wall of Honor that now includes a plaque to posthumously honor Thomas M. Venino, Sr. NORTH BERGEN – Hackensack Meridian Health Palisades Medical Center has posthumously honored Thomas M. Venino, Sr., Esq., during a special Wall of Honor dedication ceremony in the hospital’s main lobby.Members of the Venino family, board members and team members all gathered together to pay tribute to Venino, described as as a well-loved and respected member of the Palisades family.“Mr. Venino will now be perpetually memorialized as a member of the Wall of Honor for his extraordinary efforts in advancing the mission of Palisades Medical Center and his many contributions to foster exceptional medical care for all members of the community,” said Anthony J. Passannante Jr., M.D., FACC, acting president of Hackensack Meridian Health Palisades Medical Center.On Sept. 10, 1978, Venino and a group of committed volunteers from the North Hudson-South Bergen community helped fulfill a longstanding dream. What had once been North Hudson Hospital was relocated to a new home on the North Bergen waterfront – the site of the new Palisades Medical Center.“Mr. Venino and the other founders did everything that needed to be done to ensure that the hospital’s doors were open to serve our community,” said Dr. Passannante. “He was instrumental in galvanizing public support, purchasing the land and providing input on needed services and programs.”In the decades to follow, Tom and his late wife, Joan, served in many volunteer leadership roles for Palisades Medical Center and the Foundation – Tom as a member of the Board of Governors, serving as Chairman from 1978-81, and Joan as an officer and dedicated member of the Hospital Auxiliary. The Venino family’s dedicated service continues today as their son Thomas M. Venino, Jr., Esq., is a current member of the hospital’s Board of Governors.Venino, a long-time resident of Weehawken, was an attorney and community leader. Generations of the Venino family are well-known for managing Venino & Venino, Esqs, a North Bergen law firm which was established in 1913. In addition to his volunteer efforts and philanthropic support of Palisades Medical Center, Mr. Venino also supported countless non-profit and charitable organizations in our area.
The National Weather Service has issued a Flood Watch in effect for Ocean City from 1 p.m. Thursday through 4 p.m. Friday.The latest forecast calls for potentially heavy rain from Thursday afternoon through Friday afternoon. Some localized spots in the region could see as much as 3 inches, according the NWS notification. If the heaviest rain coincides with high tide, Ocean City streets could experience flooding.High tides on the bay side of Ocean City (at the Ninth Street Bridge) will be at 5:34 a.m. Thursday (predicted level for tidal waters is 5.5 feet MLW), 6:07 p.m. Thursday (4.4 feet MLW) and 6:26 a.m. Friday (5.3 feet MLW). The threshold for “minor” coastal flooding is 5.3 feet MLW.Residents and visitors are asked to closely monitor the forecast and weather conditions. Please don’t be caught off-guard. Heavy rain flooding can impact parts of the island that don’t typically experience tidal flooding.Be prepared to move vehicles. The roads closer to the beach, including Central and Wesley avenues, are at higher elevation. These roads also offer the safest routes of travel across the length of the island.For your safety and the protection of your vehicle and neighboring properties, never attempt to drive through flood waters, and do not drive around barricades.For Police and Fire Department emergencies, call 911. For non-emergencies, call 609-399-9111. Flood watch for Thursday and Friday. (Courtesy National Weather Service)
<a href=”https://www.youtube.com/watch?v=P3mHLpZg1CA” rel=”nofollow” target=”_blank”> <img src=”https://img.youtube.com/vi/P3mHLpZg1CA/0.jpg” alt=”0″ title=”How To Choose The Correct Channel Type For Your Video Content ” /> </a> Within minutes after birth, every infant in the United States undergoes a battery of tests designed to diagnose a host of conditions, including sickle cell disease.Thousands of children born in the developing world, however, aren’t so lucky, meaning many suffer and die from the illness each year.A.J. Kumar hopes to put a halt to at least some of those deaths.Kumar, a postdoctoral fellow who received his Ph.D. from the Graduate School of Arts and Sciences this year, worked with colleagues in the lab of Professor George Whitesides and other co-authors to develop a test for sickle cell disease that costs as little as 50 cents and provides results in just 12 minutes — far faster and cheaper than other methods. The test is described in a paper published this week in the Proceedings of the National Academy of Sciences.“The tests we have today work great, they have a very high sensitivity,” Kumar said. “But the equipment needed to run them costs in the tens of thousands of dollars, and they take hours to run. That’s not amenable to rural clinics, or even some cities where the medical infrastructure isn’t up to the standards we see in the U.S. That’s where having a rapid, low-cost test becomes important and this paper shows such a test can potentially work.”At a cost of about 50 cents, extensive analysis will still be needed to determine whether the test is truly accurate enough to use in the field.When run against more than 50 clinical samples — 26 positive and 26 negative — the new test showed good sensitivity and specificity for the disease, Kumar said. More extensive analysis will be needed to determine whether the test is truly accurate enough to use in the field.The method designed by Kumar is deceptively simple, and works by connecting two ideas scientists have understood for decades.The first is that blood cells affected by sickle cell are denser than normal cells, and the second is that many polymers, when mixed in water, automatically separate into layers ordered by density.Conventional methods to separate cells by density have relied on layering liquids with different density by hand. The insight arrived at by Kumar and Charles Mace (now at Tufts) was that the self-forming layers could be used to separate cells, such as red blood cells, by density.“When you mix the polymers with water, they separate just like oil and water,” Kumar said. “Even if you mix it up, it will still come back to those layers.”It wasn’t until a chance meeting with Thomas Stossel, a physician at Harvard-affiliated Brigham and Women’s Hospital, however, that Kumar believed the technology might have a real impact on sickle cell disease.“Initially, we started off working on malaria, because we thought when parasites invaded the cells, it would change their density,” he said. “But when I met Tom Stossel on a panel at the Harvard Medical School, he said, ‘You need to work on sickle cell.’ He’s a hematologist by training and has been working with a nonprofit in Zambia for the past decade, so he’s seen the need and the lack of a diagnostic tool.”When Kumar and colleagues ran tests with infected blood, the results were unmistakable. While healthy red blood cells settled in the tubes at specific levels, the dense cells from blood infected with sickle cell settled significantly lower. The band of red cells could clearly be seen by eye.Showing that the test worked was only a first step.“We wanted to make the test as simple as possible,” Kumar explained. “The idea was to make it something you could run from just a finger prick. Because these gradients assemble on their own, that meant we could make them in whatever volume we wanted, even a small capillary tube.”The design the team eventually settled on is barely larger than a toothpick. In the field, Kumar said, running the test is as simple as uncapping the tube, pricking a patient’s finger, and allowing the blood to wick into the tube.Stopping even a few sickle cell-related deaths would represent a victory, he said.“The best way to state it is in terms of the actual problem,” he said. “About 300,000 children are born every year with sickle cell disease, and the vast majority — about 80 to 90 percent — are in either Africa or India, where for the most part, they aren’t going to get access to the current screening tests.“There were studies recently that showed in sub-Saharan Africa, between 50 and 90 percent of the children born with sickle cell disease die before the age of 5,” he continued. “Whereas in the U.S. people don’t die from this disease as children, they can still live a full life. So my hope is that if this test is effective, it can make some small dent in those numbers.”
Harvard University has entered into an exclusive license and research collaboration agreement with Merck (known as MSD outside the United States and Canada) to further the development of small-molecule therapeutics for leukemia and other cancers. The novel compounds, developed in the laboratory of Harvard scientist Matthew Shair, offer an innovative approach to cancer treatment, targeting enzymes that regulate transcription.Acute myeloid leukemia (AML) is the most common form of acute leukemia, with an estimated 20,800 new cases in the United States in 2015. Moreover, AML accounts for the largest number of leukemia-related deaths, with a five-year overall survival rate of only approximately 26 percent.Shair, a professor in Harvard’s Department of Chemistry and Chemical Biology, has discovered a novel therapeutic strategy for treating AML, namely to inhibit enzymes that regulate the transcription of key genetic programs that are altered in AML and other cancers. With support from Harvard’s Blavatnik Biomedical Accelerator, Shair’s laboratory has developed highly selective and potent small molecules, with favorable pharmaceutical properties, that are now poised for advancement toward clinical trials.Merck will take over development of the candidate therapeutics and will engage in a research collaboration with the Shair laboratory to further investigate the biology of transcriptional regulator enzymes.“Accelerator funding over the course of several years has enabled my laboratory to advance some of our experimental compounds to a relatively late stage of preclinical development,” said Shair. “It’s gratifying to have discovered a new biological target in the fight against AML, but even more fulfilling to have created a promising weapon against it.”Graphic by Judy Blomquist/Harvard StaffUnder the terms of the license agreement, Merck will pay to Harvard an up-front fee of $20 million and will be responsible for development, including clinical development, and for worldwide commercialization of products. The University is also eligible to receive development and commercialization milestone payments, as well as tiered royalties on any resulting products. The compensation, which acknowledges the value Harvard and the Blavatnik Biomedical Accelerator have created, will support future groundbreaking research.“This recent agreement with the Shair laboratory is rooted in our belief that collaboration is the cornerstone for improving cancer care and driving innovation. It is the partnership among industry and academia that is truly critical to transforming cancer treatment and advancing the care for patients with difficult-to-treat blood cancers, such as acute myeloid leukemia,” said Dr. Eric Rubin, vice president and therapeutic area head, oncology early stage development, Merck Research Laboratories.The Blavatnik Biomedical Accelerator, administered by Harvard’s Office of Technology Development, supports the University’s innovative, early-stage life science research to promote the development of important biomedical advances that will improve health care and benefit society.“University researchers bring a great degree of creativity and innovation to the toughest challenges in human medicine,” said Isaac T. Kohlberg, Harvard’s senior associate provost and chief technology development officer. “Professor Shair’s inventive leukemia research, with funding from the Blavatnik Biomedical Accelerator, has reached a stage of development that is unusual in most universities but of great interest to the health care industry and ultimately to patients. His work could change the way clinicians treat a major disease.”
Chelsea is a possible destination for Borussia Dortmund’s Jadon Sancho (Picture: Getty Images)‘Three years…Chelsea said it would be impossible, so for now there’s this difficulty, but nothing is impossible.‘We don’t know what can happen, suddenly we could make a deal and get it right. ‘But what I can say today is that my contract is going over and I will be free to negotiate with any team.’More: Arsenal FCArsenal flop Denis Suarez delivers verdict on Thomas Partey and Lucas Torreira movesThomas Partey debut? Ian Wright picks his Arsenal starting XI vs Manchester CityArsene Wenger explains why Mikel Arteta is ‘lucky’ to be managing ArsenalFrank Lampard could be looking to fill Willian’s vacancy with Borussia Dortmund wonderkid Jadon Sancho.The Blues are in the running for the 20-year-old’s signature, alongside Manchester United and Liverpool, and are reportedly ready to meet his £120million asking price.MORE: Chelsea warned against signing Man Utd transfer targets Jadon Sancho and Jude BellinghamMORE: Pierre-Emerick Aubameyang and Alexandre Lacazette will leave Arsenal this summer, predicts Kevin CampbellFollow Metro Sport across our social channels, on Facebook, Twitter and Instagram.For more stories like this, check our sport page. Willian has spent seven years at the club (Picture: Getty Images)Willian has revealed contract negotiations with Chelsea have come to a standstill, leaving him free to talk to interested parties Arsenal and Tottenham.The Brazil international’s current deal at Stamford Bridge is set to expire this summer, and his request for a three-year extension has been shut down by the club.Willian has been a loyal servant since joining from Shakhtar Donetsk in 2013, but as he approaches the age of 32, and with plenty of competition in his position, he is reassessing his options. The winger has previously stated his desire to remain in London, opening the door to a move to the Gunners or Spurs – with the latter offering him a chance to be reunited with former boss Jose Mourinho.AdvertisementAdvertisementADVERTISEMENTWillian told Fox Sports: ‘Everyone knows that my contract ends now in a few months, so the renewal is really a difficult thing to happen.‘I think it will be very difficult for me to renew because Chelsea offered me two years, I asked for three and it ended there, we don’t talk anymore, we didn’t negotiate anymore.Read the latest updates: Coronavirus news live Willian ‘free to negotiate’ with Arsenal and Tottenham as Chelsea contract talks stall Advertisement Comment Metro Sport ReporterFriday 3 Apr 2020 11:46 amShare this article via facebookShare this article via twitterShare this article via messengerShare this with Share this article via emailShare this article via flipboardCopy link6.4kShares Advertisement
Arteta was named as someone who had broken the rules (Picture: Getty Images)Wilder hopes the rules will be scrapped in due course.‘I hope we don’t keep them,’ he added. ‘Let’s not worry about the beautiful game that’s been with us for years and stood the test of time.More: Arsenal FCArsenal flop Denis Suarez delivers verdict on Thomas Partey and Lucas Torreira movesThomas Partey debut? Ian Wright picks his Arsenal starting XI vs Manchester CityArsene Wenger explains why Mikel Arteta is ‘lucky’ to be managing Arsenal‘I understand a little bit of change now and again is good – the backpass rule was great – but I’m not sure the rule changes this year have given the game a big boost and improved it.’Sheffield United face Wolves on Wednesday, while Arsenal take on Leicester on Tuesday night.Should Premier League drinks breaks be scrapped?Yes0%No0%Share your resultsShare your resultsTweet your resultsFollow Metro Sport across our social channels, on Facebook, Twitter and Instagram. For more stories like this, check our sport page. Comment Metro Sport ReporterTuesday 7 Jul 2020 11:03 amShare this article via facebookShare this article via twitterShare this article via messengerShare this with Share this article via emailShare this article via flipboardCopy link1kShares Wilder accused the bigger clubs of bending the rules (Picture: AFP via Getty)Chris Wilder has bemoaned big clubs breaking the rules on giving team talks during drinks breaks and highlighted Mikel Arteta as a key offender during Arsenal’s recent FA Cup win over Sheffield United. The Sheffield United manager was opposed to rule changes that saw drinks breaks and the option of five substitutions brought in as part of Project Restart. And he fumed at the likes of Arteta cynically using the new guidelines to his side’s advantage.‘We were told against Arsenal we weren’t allowed before the game to give team talks and then I saw Mikel gather his troops and start delivering a team talk and I thought that rule, that directive we got from the Premier League, has gone straight out the window,’ said Wilder.AdvertisementAdvertisementADVERTISEMENT‘It’s obvious to everybody what’s going off.“If you look, there aren’t many people having a drink, they’re having a little sip and there’s quite a lot of huddling going on and managers and coaches getting into the players.’ Advertisement Advertisement Chris Wilder accuses Mikel Arteta of breaking the rules after Arsenal beat Sheffield United
Vodafone closed the DC plan to all members, effective 31 December 2019.This is the latest DC scheme to have joined LifeSight. Only a few days ago the UK pension scheme for the IT services and solutions provider Fujitsu announced it had moved its DC members into LifeSight.With the rise of DC master trusts as a mainstream pensions vehicle for millions of people, they’ve come under much greater focus, said the Pensions Administration Standards Association (PASA).Additional regulation and authorisation requirements are now in place to ensure master trusts are robust enough to “stand the test of time”, the association said.“It’s imperative any master trust transition, be it between master trusts or between single employer DC schemes and master trusts, follows not only the prescriptive legislation but also industry best practice.”Last November PASA published the Master Trust Transition Guidance, in which in intended to provide a framework for good practice transitions between master trusts, to assist employers, trustees and advisers, ensuring members’ benefits are correctly recorded and administered. The Vodafone UK Defined Contribution Pension (DC) Plan has started to contribute into LifeSight, a master trust run by Willis Towers Watson.After taking investment and legal advice, and listening to current members’ feedback, the trustees have decided it will also transfer all members’ existing accounts in the DC plan to LifeSight, the telecommunications company announced.This includes deferred members’ DC plan accounts – for members who have built up savings but who have now opted out, or who no longer work for Vodafone.Once the transfer has taken place, the DC plan will be wound up.
Peru’s worst political crisis in twodecades threatens unrest in the world’s No. 2 copper producer and one of theregion’s most robust economies. Peruvian President Martin Vizcarra speaks during the 4th Pacific Alliance Summit in Lima, Peru on July 6. REUTERS/GUADALUPE PARDO/FILE PHOTO Vizcarra vowed to call new legislativeelections to let voters weigh a dispute he said stymied his bid to stamp outgraft in the ruling class. LIMA – Peruvian President MartinVizcarra dissolved Congress on Monday to end a yearlong battle with rightwinglawmakers over his anti-graft campaign, but rebel legislators refused to leavethe chamber as protests against them started across the country. Opposition representatives cried“Dictator” after Vizcarra invoked a constitutional article allowing presidentsto dissolve the Congress, and immediately voted to declare him temporarilysuspended, naming Vice President Mercedes Araoz to replace him.(Reuters)
Franklin County High School Boys Varsity Tennis falls to Richmond High School 5-0.Varsity:#1 Singles Jack Stirn 6-2, 2-6, 3-6 vs. Kyle Hollingsworth#2 Singles Brant Ertel 3-6, 6-3, 1-6 vs. Joey Chimenti#3 Singles Nick Wendel 3-6, 0-6 vs. Levon Jordan#1 Doubles Lonnie Schwartz & Will Wade 5-7, 5-7 vs. Cliff Hazelbaker & Jaden Hollingsworth#2 Doubles Landen Wuestefeld & Tanner Weartz 2-6, 6-7(4-7) vs. Mark Brunton & Jaime Perez-OrdunoJunior Varsity:Travis Schwartz 2-8 vs. Jackson CornettTravis Schwartz 4-6 vs. Connor DrookCourtesy of Wildcats Coach Dylan Little.The North Decatur Girls Golf team competed at North Branch (Bridge) against Morristown in the first home match of the season. The Chargers came out victorious with a team total of 243-257. Katy Kinker was the match medalist with a score of 52.The team also celebrated the 4 seniors: Katy Kinker, Laronda Schwartz, Kenda Sieg, and Rilie Sieg. Kenda and Rilie each shot their personal best of 65 and 64 respectively.Individual Scores:Katy Kinker: 52Laronda Schwartz: 62Kenda Sieg: 65Rilie Sieg: 64Courtesy of Chargers Coach Madeline Childress.The 7th Grade Batesville Middle School Volleyball team notched their first win of the season by defeating a talented South Ripley squad. Much improvement was displayed in the areas of serving, teamwork, and hustle among all players. Scores were Batesville 25-18; 18-25; 15-7.Reesa Zimmerman scored 8 points including 3 aces while connecting on 12 of 14 serves. Grace Walter contributed 6 service points including 3 aces from the service line to help the team. Walter was also strong at the net with a match-high 8 kills in 13 swings. Zimmerman contributed 4 kills in 7 attempts to spark the offense. Jade Martin, Ashlee Sparks, and Anya Richey turned in solid performances in the back row with scrappy defense in pivotal points of the game. Addison Luers dished out 10 assists from her setting position demonstrating good judgment throughout the match. The team’s record improves to 1-2.The girls will head to Greendale on Thursday and hope to keep the momentum going. Great job, ladies!Courtesy of Bulldogs Coach Shelly Prickel.The BMS 8th Grade Volleyball team suffered their first loss of the season to South Ripley: 25-24, 25-22.It was a tight match and the team never gave up. Earning top server was Molly Meer with 7 points. Annie Negovetich added 6 points. Eva Struewing & Ava Powner each earned 4 points. Sophie Gesell added 5 kills from the front row. Molly Meer earned 3 kills. While Ava Powner & Annie Negovetch each had 2 kills. Lydia Haskamp had a stuff block.Courtesy of Bulldogs Coach Angie Ehrman.The North Decatur Lady Chargers 7th grade Volleyball team came from behind to win the game, after losing the 1st match to the St Louis Cardinals 12-25, 25-23, 15-9. They rallied in the 2nd and 3rd match with better serving and communication. The leading server was Joe Whitaker with 6 pts, next was Annie Waechter and Libby Crawford both with 5 pts each.Courtesy of Chargers Coach Molly Waechter.North Decatur Girls 8th Grade Volleyball beat St. Louis 25-13, 25-6.‘Another great victory by the 8th grade Lady Chargers! 2-0 and going strong!’ Chargers Coach Becky Bingham.The St. Louis Lady Cardinals hosted the North Decatur Chargers for our first home games.Our 7th grade game went into 3 sets leaving us a bit short for the win. Playing a solid first game with a final score of 25-12, but falling short the next two with scores of 25-23, and 15-9. Getting SLS points were Gina Grote with 10pts 4 aces, Campbell Miles with 6pts 1 ace, Ella King with 5pts 2 aces, Ava Hollins with 4pts, Bridget Lohmueller with 2pts, and Olivia Leising with 1pt. Nice job ladies.The 8th grade games we fell short in the first two sets. Final scores were 25-13 and 25-6. Scoring points for SLS were Rachel Suttmann with 4pts 2 aces, Ashley Hunter with 2pts 1 ace, Felicity Brelage with 2pts, and both Meg Ritter and Cora Roth bringing 1pt each. North had a really good serving team that was able to place the ball on our court. We kept making adjustments, but in the end it wasn’t enough. Keep working hard ladies the improvements are being made.Courtesy of Cardinals Coach Erin Trenkamp.The Batesville JV Football team beat Jennings County Panthers Monday night 14 -12. The Bulldogs started the game off with a long drive that ended with a 1 yard touchdown run by Evan Williamson. Jennings County scored shortly before halftime to make the score 6 -6 at the break.Jennings Co. scored first in the second half to take a 12 – 6 lead but was stopped on the 2 point conversion by a Carter Bohman interception. Batesville tied the score on a great one handed 30 yard TD catch by Jonathan Buschle from QB Chris Lewis. Deacon Hamilton ran in the two point conversion to give the Bulldogs the lead.The Panthers last drive of the night ended with a Buschle interception and the Bulldogs took a knee to run out the clock.Courtesy of Bulldogs Coach Tony Gausman.The Batesville High School girls’ volleyball team traveled to Franklin County on Tuesday to take on the Wildcats. The reserve team lost in two games, 25-16 and 25-18. Belle Westerfeld went 11 for 11 in serving with two of those serves being aces. Maggie Wilson led the team in serve-receive. The varsity team won in three sets. 25-17, 25-18, and 25-12. The next game will be on Thursday, August 27 at East Central High School. Courtesy of Bulldogs Coach Vickie Heil.