San Beda took another victory after overcoming archrival Colegio de San Juan de Letran, 80-76, in overtime in the NCAA Season 94 men’s basketball tournament Friday at Filoil Flying V Centre.ADVERTISEMENT ‘High crimes and misdemeanors’: Trump impeachment trial begins LATEST STORIES Sports Related Videospowered by AdSparcRead Next DepEd’s Taal challenge: 30K students displaced In fight vs corruption, Duterte now points to Ayala, MVP companies as ‘big fish’ Lights inside SMX hall flicker as Duterte rants vs Ayala, Pangilinan anew View comments MOST READ Judy Ann’s 1st project for 2020 is giving her a ‘stomachache’ John Quinto had 21 points, 11 rebounds, and four assists for the Knights while JP Calvo had 14 points and six assists. Nadine Lustre’s phone stolen in Brazil Don’t miss out on the latest news and information. For the complete collegiate sports coverage including scores, schedules and stories, visit Inquirer Varsity. Carpio hits red carpet treatment for China Coast Guard PLAY LIST 02:14Carpio hits red carpet treatment for China Coast Guard02:56NCRPO pledges to donate P3.5 million to victims of Taal eruption00:56Heavy rain brings some relief in Australia02:37Calm moments allow Taal folks some respite03:23Negosyo sa Tagaytay City, bagsak sa pag-aalboroto ng Bulkang Taal01:13Christian Standhardinger wins PBA Best Player award The Red Lions not only one-upped the Knights again, they also stretched their perfect run to five games in the season while Letran slipped to 4-2.Robert Bolick sizzled for the defending champions with 20 points, 11 rebounds, and six assists while Donald Tankoua had 11 points and 13 boards.FEATURED STORIESSPORTSGinebra beats Meralco again to capture PBA Governors’ Cup titleSPORTSAfter winning title, time for LA Tenorio to give back to Batangas folkSPORTSTim Cone still willing to coach Gilas but admits decision won’t be ‘simple yes or no’“As what I’ve said, it will be a tough game against Letran, it’s really the rivalry worth watching,” said San Beda head coach Boyet Fernandez. “The coaches of Letran did a good job on this game, we should’ve won in regulation, just credit to Letran.”AC Soberano was the main man for the Red Lions in the overtime period where he scored all six of his points to help the defending champions outscore the Knights, 11-6. Halep doubles up in Montreal by destroying Williams in straight sets Gov’t in no rush to rescue animals in Taal Peza offers relief to ecozone firms Palace OKs total deployment ban on Kuwait OFWs
Alzheimer’s disease is expected to triple in prevalence by 2050, affecting 115 million people worldwide. There’s no cure or treatment yet for the fatal neurodegenerative condition, but many physicians and scientists suggest that drugs that have failed so far will work if given much earlier, a strategy that requires diagnosing the disease before symptoms develop. Now, a research team has discovered a group of molecules in the blood that they say can predict with 90% accuracy whether older people will develop the disease over the course of 2 to 3 years. Although such a test is not ready for general use, and may never be, the technique could still help recruit people most at risk of developing Alzheimer’s into clinical trials of possible treatments.Beyond an autopsy analysis of a person’s brain, two accepted methods of diagnosing Alzheimer’s disease exist at present, says Douglas Galasko, a neuroscientist at the University of California (UC), San Diego, School of Medicine. One technique uses brain imaging to detect the hallmark protein found in plaques in brain tissue which marks the disorder. The other measures levels of these proteins by extracting fluid from the spinal cord. Few people wish to undergo that painful procedure, however, and because both techniques are expensive and not terribly accurate, particularly at the earliest stages of Alzheimer’s, researchers have spent decades looking for a less invasive, more affordable blood-based test. So far, however, these efforts have produced “no success,” Galasko says.To ferret out blood molecules that might signal the onset of Alzheimer’s disease in elderly people, a team from Georgetown University and several other institutions recruited several hundred senior citizens age 70 and up from retirement communities in New York and California. They took blood samples and shipped them on ice to a lab with a mass spectrometer in order to precisely quantify the blood samples’ chemical makeup.Sign up for our daily newsletterGet more great content like this delivered right to you!Country *AfghanistanAland IslandsAlbaniaAlgeriaAndorraAngolaAnguillaAntarcticaAntigua and BarbudaArgentinaArmeniaArubaAustraliaAustriaAzerbaijanBahamasBahrainBangladeshBarbadosBelarusBelgiumBelizeBeninBermudaBhutanBolivia, Plurinational State ofBonaire, Sint Eustatius and SabaBosnia and HerzegovinaBotswanaBouvet IslandBrazilBritish Indian Ocean TerritoryBrunei DarussalamBulgariaBurkina FasoBurundiCambodiaCameroonCanadaCape VerdeCayman IslandsCentral African RepublicChadChileChinaChristmas IslandCocos (Keeling) IslandsColombiaComorosCongoCongo, The Democratic Republic of theCook IslandsCosta RicaCote D’IvoireCroatiaCubaCuraçaoCyprusCzech RepublicDenmarkDjiboutiDominicaDominican RepublicEcuadorEgyptEl SalvadorEquatorial GuineaEritreaEstoniaEthiopiaFalkland Islands (Malvinas)Faroe IslandsFijiFinlandFranceFrench GuianaFrench PolynesiaFrench Southern TerritoriesGabonGambiaGeorgiaGermanyGhanaGibraltarGreeceGreenlandGrenadaGuadeloupeGuatemalaGuernseyGuineaGuinea-BissauGuyanaHaitiHeard Island and Mcdonald IslandsHoly See (Vatican City State)HondurasHong KongHungaryIcelandIndiaIndonesiaIran, Islamic Republic ofIraqIrelandIsle of ManIsraelItalyJamaicaJapanJerseyJordanKazakhstanKenyaKiribatiKorea, Democratic People’s Republic ofKorea, Republic ofKuwaitKyrgyzstanLao People’s Democratic RepublicLatviaLebanonLesothoLiberiaLibyan Arab JamahiriyaLiechtensteinLithuaniaLuxembourgMacaoMacedonia, The Former Yugoslav Republic ofMadagascarMalawiMalaysiaMaldivesMaliMaltaMartiniqueMauritaniaMauritiusMayotteMexicoMoldova, Republic ofMonacoMongoliaMontenegroMontserratMoroccoMozambiqueMyanmarNamibiaNauruNepalNetherlandsNew CaledoniaNew ZealandNicaraguaNigerNigeriaNiueNorfolk IslandNorwayOmanPakistanPalestinianPanamaPapua New GuineaParaguayPeruPhilippinesPitcairnPolandPortugalQatarReunionRomaniaRussian FederationRWANDASaint Barthélemy Saint Helena, Ascension and Tristan da CunhaSaint Kitts and NevisSaint LuciaSaint Martin (French part)Saint Pierre and MiquelonSaint Vincent and the GrenadinesSamoaSan MarinoSao Tome and PrincipeSaudi ArabiaSenegalSerbiaSeychellesSierra LeoneSingaporeSint Maarten (Dutch part)SlovakiaSloveniaSolomon IslandsSomaliaSouth AfricaSouth Georgia and the South Sandwich IslandsSouth SudanSpainSri LankaSudanSurinameSvalbard and Jan MayenSwazilandSwedenSwitzerlandSyrian Arab RepublicTaiwanTajikistanTanzania, United Republic ofThailandTimor-LesteTogoTokelauTongaTrinidad and TobagoTunisiaTurkeyTurkmenistanTurks and Caicos IslandsTuvaluUgandaUkraineUnited Arab EmiratesUnited KingdomUnited StatesUruguayUzbekistanVanuatuVenezuela, Bolivarian Republic ofVietnamVirgin Islands, BritishWallis and FutunaWestern SaharaYemenZambiaZimbabweI also wish to receive emails from AAAS/Science and Science advertisers, including information on products, services and special offers which may include but are not limited to news, careers information & upcoming events.Required fields are included by an asterisk(*)Over the next 3 years, the researchers tracked the seniors’ mental health, and identified 53 people with mild cognitive impairment or Alzheimer’s disease, 18 of whom had not displayed any symptoms at the beginning of the study. At the 3-year mark, they returned to the analyses of the blood samples and compared those of the people who had developed symptoms of Alzheimer’s disease with 53 of the elderly people from the group who remained healthy. In the group whose mental health had declined, there were significant alterations in the blood levels of 10 different chemicals, including fatty molecules called phospholipids, which help keep cell membranes in the brain and body intact, the team reports online today in Nature Medicine.To check that its observations weren’t just a random event, the team tested whether the same altered pattern could predict whether 41 other elderly people from the same retirement communities had developed Alzheimer’s disease, and found that it hit the mark 90% of the time. Despite these encouraging findings, senior author Howard Federoff, a neuroscientist at Georgetown University in Washington, D.C., says the test needs much more validation. “This is a new observation, and it’s imperative that it be extended and replicated on an independent group of individuals.”Others are equally cautious. “We won’t know if it’s going to be a big deal or not” until other groups replicate the study, agrees Michael Weiner, a neuroscientist at UC San Francisco. The population of people with Alzheimer’s disease is so diverse, and is fraught with so many health problems, that it may turn out that although the test is good at detecting people who are at risk for cognitive decline, it will pick up too many other conditions in the process to be useful as a diagnostic tool. If that’s the case, the test could still be used to screen people for preventative clinical trials of Alzheimer’s drugs for the disease, he says.That Federoff and colleagues validated their findings in an independent group of elderly people is “impressive,” says Robert Green, a medical geneticist at Harvard University. Many such studies “have turned out to be a flash in the pan,” he says, but the new study “is more sophisticated than most.”*Correction, 17 March, 4:06 p.m.: This story has been corrected to reflect that only one of Alzheimer’s two hallmark protein deposits can currently be imaged in the brain for diagnostic purposes.